Doctoral Dissertation Themes

List of doctoral dissertation themes for the academic year 2022/2023

Bioorganic Chemistry

• Novel stereoselective rearrangements mediated by small molecules
  Supervisor: Dr. rer. nat. Mgr. Ing. Tomáš Hodík

Pharmaceutical Chemistry

• Study of derivatives based on nitrogen heterocycles as potential antimicrobial agents
  Supervisor: prof. PharmDr. Martin Doležal, Ph.D.
  Consultant: PharmDr. Marta Kučerová, Ph.D.

Pharmaceutical Analysis

• Automation of methodologies based on luminiscence detection for analytes of biological and pharmaceutical interest
  Supervisor: doc. PharmDr. Hana Sklenářová, Ph.D.
  Consultant: Dr. Burkhard Horstkotte
• Automation of sample pre-treatment based on extraction procedures using sequential injection analysis III
  Supervisor: doc. PharmDr. Petr Chocholouš, Ph.D.
• Host proteins detection in antobody biotherapeutics
  Supervisor: doc. PharmDr. Hana Sklenářová, Ph.D.
  Consultant: PharmDr. Juraj Lenčo, Ph.D.
• Chiral separations of borane clusters
  Supervisor: doc. PharmDr. Radim Kučera, Ph.D.
• Real time monitoring of content of biologically active substances using flow methods
  Supervisor: doc. PharmDr. Hana Sklenářová, Ph.D.

Pharmacognosy and Nutraceuticals

• Isolation and biological activity of selected indole alkaloids
  Supervisor: PharmDr. Marcela Šafratová, Ph.D.
  Consultant: doc. PharmDr. Jakub Chlebek, Ph.D.
• Substances of natural origin useful in the prevention of cardiovascular diseases
  Supervisor: doc. Ing. Kateřina Macáková, Ph.D.

Pharmacology and Toxicology

• Effect of nucleoside-derived antivirals on nucleoside homeostasis and modulation of inflammatory processes in the placenta
  Supervisor: doc. PharmDr. Lukáš Červený, Ph.D.
• Perspectives in nuclear receptors modulation with novel compounds
  Supervisor: prof. PharmDr. Petr Pávek, Ph.D.
• Use of cannabis in pregnancy; effect on placental functions
  Supervisor: prof. PharmDr. František Štaud, Ph.D.

Xenobiochemistry and Pathobiochemistry

• Epigenetic regulation of carbonyl-reducing enzymes in parasitic nematodes
  Supervisor: doc. Ing. Petra Matoušková, Ph.D.