Doctoral Dissertation Themes

List of doctoral dissertation themes for the academic year 2024/2025

Bioanalytical Methods

• Automation of QuEChERS-like preparation for modern separation techniques
  Supervisor: doc. PharmDr. Hana Sklenářová, Ph.D.
  Consultant: doc. Burkhard Horstkotte, M.Sc., Dr.
• Green solvent extraction for pharmaceutical and contaminant analysis
  Supervisor: doc. PharmDr. Hana Sklenářová, Ph.D.
  Consultant: doc. Burkhard Horstkotte, M.Sc., Dr.

Pharmaceutical Analysis

• Automated methodologies for analytes of biological and pharmaceutical interest based on luminiscence detection
  Supervisor: doc. PharmDr. Hana Sklenářová, Ph.D.
  Consultant: doc. Burkhard Horstkotte, M.Sc., Dr.
• Development of one- and two-dimensional chromatographic methods coupled to mass spectrometry for proteomic analyses and analysis of protein biopharmaceuticals
  Supervisor: doc. PharmDr. Hana Sklenářová, Ph.D.
  Consultant: PharmDr. Juraj Lenčo, Ph.D.

Pharmaceutical Technology

• Evaluation of skin barrier formation using model systems based on lamellar bodies
  Supervisor: doc. PharmDr. Andrej Kováčik, Ph.D.

Pharmacognosy and Nutraceuticals

• Arundo donax L. alkaloids and their biological activity.
  Supervisor: doc. PharmDr. Jakub Chlebek, Ph.D.
• Biological activity of Amaryllidaceae alkaloids and their semisynthetic derivatives in connection with Alzheimer´s disease
  Supervisor: prof. Ing. Lucie Cahlíková, Ph.D.

Pharmacology and Toxicology

• Quantitative prediction of drug metabolism mechanism
  Supervisor: Eugen Hruška, Ph.D.
• Study on the role of pharmacokinetic mechanisms in the anticancer drug resistance and possibility of their modulation
  Supervisor: doc. RNDr. Jakub Hofman, Ph.D.