Pharmaceutical Technology

The compulsory subject in the 4th section of study of Pharmacy.

Pharmaceutical technology education is focused on dosage forms formulation with emphasis on their classification, properties and the use of excipients, elucidating composition and structure of dosage forms in technological and biopharmaceutical context. The use of specific pharmaceutical manufacturing procedures and quality control methods for dosage forms is included.

The practical training enable students to gain the basic skills necessary for compounding of preparations in pharmacies as well as in the large-scale manufacturing and the evaluation of properties of pharmaceutical products. Seminars improve knowledge of specific methods used in the formulation and/or the evaluation of pharmaceutical preparations.

The subject is concluded by passing the exam and it is included in the Final State Examination.

Syllabus

1) Dosage Forms

  • Dosage forms and their classification

  • Pharmaceutical excipients

  • Biopharmaceutical principles in dosage forms

  • Pharmaceutical dispersion systems

  • Liquid dosage forms

  • Semisolid dosage forms

  • Solid dosage forms

  • Sterile dosage forms

  • Aerodispersions. Inhalation preparations

  • Modified release drug delivery systems

  • Targeted drug delivery systems

2) Manufacturing operations in pharmaceutical technology

  • Water production

  • Filtration

  • Comminution. Milling

  • Mixing. Homogenization

  • Drying, Freeze Drying

  • Sterilization

3) Quality control and stability of dosage forms

  • Good manufacturing practice

  • Stability of dosage forms.

  • Pharmaceutical packaging

  • Rheology

  • Granulometry

  • Disolution tests

  • Uniformity of dose

Literature

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