Technology of Natural Drugs

This subject provides information about procedures and apparatuses used in the manufacturing of drugs of natural origin. It deals with the preservation, storage and mechanical adjustments of biological material, with the extraction, isolation and purification of pharmaceutically important substances of plant and animal origin, and with the quality control of raw materials and final products. Attention is also paid to pharmacopoeial regulations, and principles of good manufacturing practice.

Syllabus

Lectures

  • Preservation and storage of biological material
  • General concept and purposes of grinding, equipment for grinding
  • Separation and isolation of plant constituents, parameters influencing extraction procedures, equipment for extraction
  • Basic principles of natural product purification
  • Isolation of cardiac glycosides from Digitalis purpurea and Digitalis lanata
  • Isolation of flavonolignans from Silybum marianum
  • Isolation of ergot alkaloids
  • Manufacturing of medicinal teas
  • Natural drugs of animal origin
  • Quality control
  • Good manufacturing practice

Literature

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