Advanced Organic Chemistry

The aim of this subject is to extend students' knowledge of organic chemistry with focus on approaches used in research and development of biologically active substances.

Syllabus

  1. General principles in drug development
  2. Retrosynthetic analysis I
  3. Retrosynthetic analysis II
  4. Protective groups
  5. Combinatorial chemistry
  6. Basic molecular modelling
  7. Molecular modelling – practical course
  8. Quantitative structure-activity relationships (QSAR)
  9. Spectral methods in structural analysis
  10. Chemistry of sphingolipids
  11. Transdermal drug delivery
  12. Platinum cytostatics

Literature

© 2019 Charles University, Faculty of Pharmacy in Hradec Králové | Website information