Pathological Physiology for Pharmacists

This subject comprises the general knowledge of pathological morphology and physiology, followed by the fundamentals of pathophysiological and all clinical manifestations of diseases the relation to the main body systems (blood, circulatory, respiratory, etc.).


Introduction to pathology

  • basic terminolgy
  • mechanisms of cell injury
  • diseases caused by physical and chemical agents
  • diseases caused by biological agents

General pathology

Regressive processes, metabolic disorders, malformations

  • degenerative processes associated with abnormal changes of proteins, lipids and carbohydrates
  • cell death and necrosis
  • inherited metabolic disorders

Inflammations and repair

  • acute inflammation – cellular events
  • chemical mediators of inflammation
  • chronic inflammation
  • systemic effects of inflammation
  • cellular adaptations
  • repair (by first and second intention)
  • immunopathology


  • aetiology and pathogenesis of neoplasms
  • biology of tumour growth, mechanisms of invasion and metastasis
  • classification and nomenclature of neoplasms

Systemic pathology


  • RBC deficiency (anaemia), functional characteristics, classification of anaemias
  • polyglobulias
  • porphyries
  • WBC disorders, malignant lymphomas
  • disorders of haemostasis, haemorrhagic disorders. Thrombosis embolism

Cardiovascular pathology

  • heart disorders: endocard diseases, myocard diseases (ischaemia, infarction)pericard diseases
  • valvular deformities: stenosis, insufficiency
  • dysrhythmias, heart blocks
  • congenital heart diseases
  • heart failure acute and chronic
  • arteriosclerosis
  • hypertension
  • cardiovascular shock
  • diseases of veins

Respiratory pathology

  • respiratory insufficientia, her aetiology
  • atelectasis
  • emphysema
  • obstructive airway disease, asthma bronchiale
  • pulmonary hypertension
  • pulmonary infarction
  • pulmonary oedema
  • pneumonia
  • tuberculosis
  • pleural lesions

Alimentary pathology, hepatobiliary pathology, pathology of pancreas

  • pathophysiological terminology (nausea, vomitus, anorexia, singultus, diarrhoea, obstipatio ...)
  • diseases of mouth, pharynx, oesophagus
  • diseases of stomach, duodenum, small intestine
  • diseases of colon, anus
  • hepatobiliary pathology
  • diseases of pancreas

Endocrine pathology

  • hypothalamus and neurohypophysis
  • adenohypophysis
  • thyroid gland
  • parathyroid glands
  • adrenal glands
  • islets of Langerhans
  • male and female genital systems

Renal pathology

  • glomerulonephritides
  • pyleonephritides
  • vascular renal disease
  • renal failure acute, chronic
  • pathological ingredients of urine

Diseases of muscle, bone and joints, and skin

  • myasthenia, myotonia
  • myodystrophia progressiva
  • osteoporosis, -fibrosis, -sclerosis
  • arthritides, arthroses
  • diseases of skin

Neuropathology, pathology of eye, ear, psychiatry

  • inflammatory diseases of nervous system
  • cerebral vascular disease, infarction
  • demyelinating disease (multiple sclerosis)
  • degenerative diseases (Parkinson's, Huntington's, Alzheimer's disease)
  • other diseases (m. Wilson, m. Recklinghausen, phenylketonuria, deficiency o thiamine, of B12, anoxia, hypoglycaemia)
  • basic psychiatric nomenclature
  • psychoses (endogenous, exogenous)
  • psycho neuroses (neurasthenias, hysterias, psychasthenias)
  • psychopathies
  • Pathology of infectious diseases
  • infections caused by bacteria
  • pathology of viral diseases, rickettsial infections
  • pathology of parasitic diseases

Practical training

In these lessons there is a studied matter completed and exercised by active taking part of students; the hearers have the opportunity of seeing macro models and micro preparations of pathological processes.


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