Genetics

Syllabus

DNA and chromosomes

  • structure of DNA
  • genic and nongenic DNA
  • chromosome structure in prokaryotes, viruses, and eukaryotes

Inheritance I

  • definition of terms
  • Mendel’s study of heredity
    • Mendelian laws
    • applications of Mendel’s principles
  • interaction of paired alleles – dominance, recessivity, codominance, incomplete dominance
  • the chromosomal basis of Mendelism – Morgan
  • polygenic inheritance
  • genotype-environment interaction

Inheritance II

  • population genetics
    • Hardy-Weinberg equilibrium
    • evolutionary factors
  • extranuclear heredity
  • genetic diseases

Mutations

  • gene mutations
  • chromosomal mutations
  • genomic mutations
  • mutations and diseases

Replication of DNA

  • principle of DNA replication
  • replication machine - proteins of replication fork

Expression of genetic information

  • transcription – prokaryotes, eukaryotes
  • posttranscriptional modification of mRNA, tRNA, rRNA
  • translation
  • posttranslational processing

Parasexual processes of bacteria

  • transformation
  • conjugation
  • transduction

Viruses

  • structure of virion
  • structure of bacteriophage
  • viral genome
  • reproduction of viruses - lytic and lysogenic cycle
  • retroviruses

Literature

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