Analyses of therapeutical value, consumption and need of drugs, and history of pharmacy

Clinical & Social Pharmacy and History of Pharmacy (KLINSOF-HIF)

Research group led by doc. PharmDr. Josef Malý, Ph.D. deals with various aspects of the drug life from research to the end of registration, as well as factors influencing the need and consumption of drugs in different population groups and, last but not least, pharmacy as a professional field. The aim of the research is to develop the methods and their application in the observing clinical and social factors influencing the therapeutic and economic value of drugs and maximizing the effect and minimizing the risks of pharmacotherapy in real practice. An important focus of the research is the analysis of pharmacotherapy in population groups that differ from the population included in drug testing in clinical trials. Research activities are carried out in two research units: Pharmacoepidemiology and Clinical Pharmacy, History of Health Care and Pharmacy.

Research of the Pharmacoepidemiology and Clinical Pharmacy unit is focused mainly on drug consumption, development of methodology and its application in the analysis of drug-related problems, research on aspects of medication taking behaviour (needs, concerns and medication adherence), analysis of pharmaceutical care indicators, and development and effectiveness of pharmacovigilance activities, and professional medicine information in clinical practice.
Research of the History of Health Care and Pharmacy unit is carried out the study of the development of pharmacy and healthcare in the Czech lands and Czechoslovakia. The research is mainly focused on pharmacy practice in the early modern period and the 20th century, healthcare and its institutional form in the early modern period, and on drugs, pharmaceuticals, and pharmacotherapy in the early modern period.

Ageing and Changes in the Therapeutic Value of Drugs in the Aged

The research group chaired by doc. PharmDr. Daniela Fialová, Ph.D. focuses on processes influencing the ageing of the organism and their specific impact on therapeutic value of drugs in older population with respect to specific geriatric syndromes and symptoms, factors associated with geriatric frailty and other determinants of ageing. Also risk factors and negative impact of inappropriate prescribing of medications in older patients are analysed in various healthcare settings.

The group is also focused on the evaluation of prevalence of complementary and alternative medicine (CAM) use, CAM attitudes, CAM regulation, and evaluation of the effectiveness and safety of CAM approaches, especially mind-body-spiritual approaches, in the treatment and prevention of chronic diseases.

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