Doctoral Dissertation Themes

Synthesis and study of compounds that modulate skin barrier permeability

Synthesis of lipid-like compounds as potential modulators of the skin barrier properties for either transdermal/dermal drug delivery or as barrier repair agents, and study of their mechanisms of action (includes ex vivo permeation experiments with human skin, evaluation of the skin barrier properties using infrared spectropy...).

Supervisor: prof. PharmDr. Kateřina Vávrová, Ph.D.

Keywords: kožní bariéra, modulátory permeace, podání léčiv

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