Wednesday 24. January 2018
Program of the conference in PDF
Lecture hall A
Joint session
Chairman: Prof. RNDr. Petr Solich, CSc.
| 8:30 - 8:45 |
Conference opening - introduction
Prof. PharmDr. Tomáš Šimůnek, Ph.D., Dean of the Faculty of Pharmacy
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| 8:45 - 9:45 |
Preparation of manuscript that is likely to be accepted in high end journal
Prof. František Švec
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9:45 - 10:00
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Coffee break (S2155)
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| 10:00 - 10:30 |
Bead injection for (bio)chemical analysis
Prof. Marcela Segundo, University of Porto, Portugal
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| 10:30 - 11:00 |
Environmental Pollutant Sensing on a Paper-Based Microfluidic Platform
Prof. Spas Kolev, University of Melbourne, Australia
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Lecture hall A
Session 1 - Bioorganic and Pharmaceutical chemistry
Chairman: Prof. PharmDr. Martin Doležal, Ph.D.
| 12:30 - 12:45 |
PYRAZINAMIDE; NOT THE END OF THE STORY
G. Bouz
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| 12:45 - 13:00 |
PREPARATION OF BENZODIAZINES WITH BRONCHODILATORY ACTIVITY
Z.R. Brožová
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| 13:00 - 13:15 |
INTRAMOLECULAR TSUJI-TROST REACTION: NEW ROUTE TO HIGHLY SUBSTITUTED PYRANONES
Z. Brůža
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| 13:15 - 13:30 |
NEW AZAPHTHALOCYANINE DARK QUENCHER USABLE IN POLYMERASE CHAIN REACTION
J. Demuth
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| 13:30 - 13:45 |
THE NOVEL LEAD CANDIDATES FOR THE TREATMENT OF ORGANOPHOSHOROUS INTOXICATION
L. Gorecki
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13:45 - 14:00
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NONTOXIC COMBRETAFURANONE ANALOGUES WITH HIGH IN VITRO ANTIBACTERIAL ACTIVITY
P. Horký
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14:00 - 14:15
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Coffee break (S2155)
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| 14:15 - 14:30 |
SYNTHESIS OF NEW SULFONATED AZAPHTALOCYANINE AND ITS PHOTOPHYSICAL AND PHOTODYNAMIC PROPERTIES
J. Kollár
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| 14:30 - 14:45 |
RHODANINE DERIVATIVES AS POTENTIAL AGENTS IN TREATMENT OF CHRONIC DIABETIC COMPLICATIONS
M. Kučerová
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| 14:45 - 15:00 |
APPROACHES TO TOTAL SYNTHESIS OF NOSTOTREBIN 6
P. Matouš
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| 15:00 - 15:15 |
FIGHTING MICROBIAL RESISTANCE – WHO IS GOING TO WIN?
O. Janďourek
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Lecture hall B
Session 2 - Pharmacognosy and Toxicology of Natural Compounds
Chairman: Doc. Ing. Lucie Cahlíková, Ph.D.
| 12:30 - 12:45 |
AMARYLLIDACEAE ALKALOIDS AS POTENT GSK 3Β INHIBITORS
D. Hulcová
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| 12:45 - 13:00 |
PHYTOCHEMICAL STUDY OF AMARYLLIDACEAE ALKALOIDS FROM NARCISSUS CV. CARLTON AND THEIR BIOLOGICAL ACTIVITY
A. Al Mamun
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| 13:00 - 13:15 |
USE OF HPCCC FOR ISOLATING ASTAXANTHIN ESTERS FROM MICROALGAE HAEMATOCOCCUS PLUVIALIS
T. Fábryová
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| 13:15 - 13:30 |
ISOLATION OF AMARYLLIDACEAE ALKALOIDS FROM ZEPHYRANTHES CITRINA
E. Kohelová
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| 13:30 - 13:45 |
NMR ELUCIDATION OF ALKALOIDS ISOLATED FROM MAGNOLIA × SOULANGEANA
J. Maříková
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13:45 - 14:00
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Coffee break (S2155)
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| 14:00 - 14:15 |
PHYTOCHEMICAL ANALYSIS AND BIOLOGICAL ACTIVITY OF SELECTED MEDICINAL PLANTS WITH A FOCUS ON TESTING THE IMMUNOMODULATORY AND TYROSINASE ACTIVITIES
R. Vrabec
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| 14:15 - 14:30 |
COPPER CHELATION ACTIVITIES OF ISOLATED COMPOUNDS FROM SILYBUM MARIANUM - STRUCTURE–ACTIVITY RELATIONSHIP
J. Karlíčková
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| 14:30 - 14:45 |
ALKALOIDS OF VINCA MINOR L. AND THEIR EFFECT ON ACTIVITY OF SELECTED ENZYMES AS BENEFIT TO PROGRESS OF ALZHEIMER'S DISEASE
M. Ločárek
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Lecture hall B
Session 3 - Pharmaceutical Technology
Chairman: Doc. PharmDr. Zdeňka Šklubalová, Ph.D.
| 15:00 - 15:15 |
MONOLAYER STUDY OF GLUCOSYLCERAMIDE-TO-CERAMIDE PROCESSING DURING SKIN BARRIER FORMATION
A. Nováčková
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| 15:15 - 15:30 |
SILK FIBROIN AND ITS APPLICATION IN PHARMACEUTICAL TECHNOLOGY
J. Kožák
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| 15:30 - 15:45 |
POLYMERIC NANOPARTICLES FOR INTRACELLULAR DELIVERY
J. Kubačková
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| 15:45 - 16:00 |
STARLIKE POLYMERIC NANOPARTICULATE DRUG CARRIERS
J. Martiška
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| 16:00 - 16:15 |
THE COMPRESSIBILITY STUDY OF PELLETS, POWDER MICROCRYSTALLINE CELLULOSE AND THEIR MIXTURES
Ž. Trpělková
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| 16:15 - 16:30 |
PRE-FORMULATION STUDIES OF LIQUISOLID SYSTEMS
B. Vraníková
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Thursday 25. January 2018
Lecture hall A
Session 4 - Pharmaceutical Analysis and Bioanalytical Chemistry
Chairmen: Prof. Marcela Segundo a Prof. Spas Kolev
| 8:30 - 8:45 |
UHPLC-MS/MS METHOD FOR MONITORING OF ARGININE METABOLISM IN CHRONIC WOUNDS
L. Javorská
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| 8:45 - 9:00 |
DEVELOPMENT OF UHPLC METHOD FOR STABILITY STUDY OF OMEPRAZOLE SUSPENSIONS
K. Kučerová
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| 9:00 - 9:15 |
CHROMATOGRAPHIC METHOD FOR THE ASSESSMENT OF VITAMIN B1 AND B6 DERIVATIVES IN WHOLE BLOOD
J. Jenčo
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| 9:15 - 9:30 |
MIXED-MODE STATIONARY PHASES: EFFECT OF MOBILE PHASE TYPE AND ITS IONIC STRENGTH ON SEPARATION
L. Chrenková
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| 9:30 - 9:45 |
ENRICHING OF PREPARED FLAT SHEET POLYSULFONE MEMBRANE FOR SEPARATION OF BIOMOLECULES WITH ANTIOXIDANT Α-TOCOPHEROL AND Α-LIPOIC ACID
M. Kohlová
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| 9:45 - 10:00 |
APPLICABILITY OF ULTRA-HIGH PERFORMANCE SUPERCRITICAL FLUID CHROMATOGRAPHY IN PHARMACEUTICAL QUALITY CONTROL
K. Plachká
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10:00 - 10:15
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Coffee break (S2155)
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| 10:15 - 10:30 |
NANOFIBROUS POLYMERS AS EXTRACTION SORBENTS IN A SAMPLE PREPARATION
H. Raabová
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| 10:30 - 10:45 |
AUTOMATED CONTINUOUS IN-SYRINGE DISPERSIVE LIQUID-LIQUID EXTRACTION AND BACK-EXTRACTION FOR THE DETERMINATION OF NITROPHENOLS IN SURFACE WATER
K. Fikarová
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| 10:45 - 11:00 |
TESTING OF ELECTROSPUN NANOFIBERS FOR ON-LINE EXTRACTION IN CHROMATOGRAPHY SYSTEMS
M. Háková
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| 11:00 - 11:15 |
STUDY OF SEPARATION BEHAVIOR OF SELECTED PHENOLIC ANALYTES
M. Hollá
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| 11:15 - 11:30 |
DEVELOPMENT AND OPTIMIZATION OF UHPLC-MS/MS METHOD FOR ANALYSIS OF HCV ANTIVIRALS IN SAMPLES ARISED FROM CELL EXPERIMENTS
J. Pavlík
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| 11:30 - 11:45 |
UHPLC-MS/MS STABILITY STUDY OF SOBUZOXANE AND ITS ACTIVE FORM - ICRF-154 IN BIOLOGICAL MATRICES
P. Reimerová
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Lunch break
| 12:45 - 13:00 |
IS SUPERCRITICAL FLUID EXTRACTION USEFUL TOOL FOR EXTRACTION OF BIOACTIVE COMPOUNDS?
V. Pilařová
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| 13:00 - 13:15 |
UHPLC-MS/MS OF A NOVEL DEXRAZOXANE ANALOGUE- JAS -2 AND ITS PRODRUG
H. Piskáčková
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| 13:15 - 13:30 |
TESTING OF NANOFIBERS AS NOVEL SORBENTS USING SEQUENTIAL INJECTION ANALYSIS SYSTEM
I. Šrámková
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| 13:30 - 13:45 |
SEQUENTIAL INJECTION DETERMINATION OF THE HERBICIDE 2,4-DICHLOROPHENOXYACETIC ACID USING PRECONCENTRATION WITH A POLYMER INCLUSION MEMBRANE
L. Zelená
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| 13:45 - 14:00 |
CANDIDA ALBICANS METABOLOMICS AND QUORUM SENSING IN HUMAN VAGINAL SWABS USING HIGH-RESOLUTION MASS SPECTROMETRY
P. Jakubec
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| 14:00 - 14:15 |
DEVELOPMENT OF CAPILLARY ELECTROPHORESIS METHOD
FOR THE CHARACTERIZATION OF PHARMACEUTICALS CONTAINING SILYMARIN COMPLEX
P. Riasová
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| 14:15 - 14:30 |
UHPLC-MS/MS ANALYSIS OF ANTIVIRAL AGENT SOFOSBUVIR FOR STUDY OF ITS TRANSPORT MECHANISM
P. Svobodová
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14:30 - 15:00
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Coffee break (S2155)
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Lecture hall A
Session 5 - Pathobiochemistry and Xenobiochemistry
Chairman: Prof. Ing. Barbora Szotáková, Ph.D.
| 15:00 - 15:15 |
GPXS, MICRORNA AND OBESITY ASSOCIATION
B. Hanousková
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| 15:15 - 15:30 |
ACUTE TOXICITY OF R-PULEGONE AND R-MENTHOFURAN IN HUMAN LIVER SLICES
T. Zárybnický
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| 15:30 - 15:45 |
IN VITRO STUDY OF DEXRAZOXANE ANALOG JAS 2 AND ITS WATER-SOLUBLE PRODRUGS
H. Jansová
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| 15:45 - 16:00 |
ROLE OF HEXOSE-6-PHOSPHATE IN PROLIFERATION AND MIGRATION OF CANCER CELLS
H. Navrátilová
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| 16:00 - 16:15 |
EVALUATION OF DRUG UPTAKE AND DEACTIVATION IN PLANT
L. Raisová Stuchlíková
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Lecture hall B
Session 6 - Pharmacology and Toxicology
Chairmen: Prof. PharmDr. František Štaud, Ph.D. a Doc. PharmDr. Přemysl Mladěnka, Ph.D.
| 8:30 - 8:45 |
OXYSTEROLS AFFECT ENDOGLIN EXPRESSION, INFLAMMATION AND DEVELOPMENT OF ENDOTHELIAL DYSFUNCTION IN HUMAN AORTIC ENDOTHELIAL CELLS
M. Vicen
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| 8:45 - 9:00 |
HIGH SOLUBLE ENDOGLIN LEVELS ACCOMPANIED BY MILD HYPERCHOLESTEROLEMIA AGGRAVATE ENDOTHELIAL DYSFUNCTION IN MOUSE AORTA
B. Vitverová
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| 9:00 - 9:15 |
PHARMACOKINETIC INTERACTIONS OF NOVEL ANTICANCER DRUGS WITH ABC DRUG EFFLUX TRANSPORTERS AND CYTOCHROMES P450
D. Vagiannis
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| 9:15 - 9:30 |
THE IN VITRO AND EX VIVO TESTING OF ANTIVIRAL DRUGS EFFECT ON RHODAMINE123 INTESTINAL ABSOPTION
O. Martinec
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| 9:30 - 9:45 |
ENTECAVIR TRANSPORT ACROSS PLACENTA AND THE ROLE OF NUCLEOSIDE TRANSPORTERS
S. Karbanová
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9:45 - 10:00
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Coffee break (S2155)
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10:00 - 10:15
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THE INHIBITORY EFFECT OF ANTIRETROVIRAL DRUGS ON THE TRANSPORT OF L-CARNITINE IN HUMAN PLACENTA
R. Karahoda
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| 10:15 - 10:30 |
NUCLEOSIDE TRANSPORTERS; ROLE IN PHARMACOKINETICS AND MECHANISMS OF REGULATION
L. Jirásková
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| 10:30 - 10:45 |
RADIOLABELED MONOCLONAL ANTIBODY RAMUCIRUMAB: IN VITRO AND IN VIVO BINDING TO THE TARGET
J. Janoušek
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| 10:45 - 11:00 |
INVOLVEMENT OF FARNESOID X RECEPTOR IN NOVEL HUMAN CELLULAR MODEL OF STEATOHEPATITIS
A. Horvátová
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| 11:00 - 11:15 |
ASSESSMENT OF THE STOICHIOMETRY OF IRON AND COPPER WITH DEHYDROSILYBIN A AND B
M. C. Catapano
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| 11:15 - 11:30 |
THE INFLUENCE OF FLAVONOIDS METABOLITES ON PLATELET AGGREGATION
L. Applová
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| 11:30 - 11:45 |
INTERGENDER DIFFERENCES IN THE VASOACTIVE EFFECT OF SELECTED ISOFLAVONOIDS AND THE THEIR COLONIC METABOLITES
T. Migkos
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Lunch break
| 12:45 - 13:00 |
INVOLVEMENT OF DRUG TRANSPORTERS IN MARAVIROC TRANSPORT ACROSS PLACENTAL BARRIER
L. Ťupová
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| 13:00 - 13:15 |
OVERCOMING DAUNORUBICIN RESISTANCE VIA ABCC1 AND AKR1C3 INHIBITION BY CYCLIN-DEPENDENT KINASE INHIBITORS
A. Šorf
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| 13:15 - 13:30 |
NOVEL RAPID BUT PRECISE SPECTROPHOTOMETRIC SCREEENING METHOD FOR DETERMINIATION OF ZINC CHELATION
V. Tvrdý
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| 13:30 - 13:45 |
CONSTITUTIVE ANDROSTANE RECEPTOR IN THE REGULATION OF XENOBIOTIC METABOLISM
J. Dušek
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| 13:45 - 14:00 |
ASPECTS OF POST-TRANSCRIPTIONAL REGULATION OF PREGNANE X RECEPTOR
T. Smutný
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| 14:00 - 14:15 |
INTERACTIONS OF ANTIRETROVIRALS WITH DRUG TRANSPORTERS; ROLE IN THE PHARMACOKINETICS
J. Řezníček
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14:15 - 14:45
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Coffee break (S2155)
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Lecture hall B
Session 7 - Clinical and Social Pharmacy
Chairmen: Prof. PharmDr. Jiří Vlček, Ph.D. a PharmDr. Daniela Fialová, PhD.
| 14:45 - 15:00 |
COLD, BUT RISING STAR OF VALUE ADDED MEDICINES IN EUROPE
J. Röder
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| 15:00 - 15:15 |
THE BIOIMPEDANCE SPECTROSCOPY APPLICATION IN PREGNANT WOMEN WITH PRETERM PREMATURE RUPTURE OF MEMBRANES
V. Josková
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| 15:15 - 15:30 |
ADJUSTMENTS IN ENERGY EXPENDITURE AND SUBSTRATE OXIDATION DURING PREGNANCY
A. Patková
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| 15:30 - 15:45 |
POTENTIALLY INAPPROPRIATE MEDICATION USE IN NURSING HOME RESIDENTS IN THE CZECH REPUBLIC: RESULTS FROM THE EU SHELTER PROJECT
S. Grešáková
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| 15:45 - 16:00 |
DRUG UTILIZATION STUDY OF ANTICOAGULANTS
S. Dvořáčková
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| 16:00 - 16:15 |
ANALYSIS OF FACTORS INFLUENCING THE RISK OF FALLS – PILOT RESULTS
J. Vosátka
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| 16:15 - 16:30 |
POTENTIALLY INAPPROPRIATE MEDICATION USE („PIM“ USE) IN OLDER PATIENTS IN A TERTIARY CARE TEACHING HOSPITAL IN SOUTH INDIA: PREVALENCE AND RISK FACTORS
D.K. Bandari - prezentuje S. Grešáková
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| 16:30 - 16:45 |
KNOWLEDGE OF DIFFERENT PHARMACY PROGRAM STUDENTS ON RATIONAL GERIATRIC PHARMACOTHERAPY
A.S.Bhagavathula
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| 16:45 - 17:00 |
CARDIOVASCULAR COMORBIDITIES AND RISK FACTORS IN ACCORDANCE WITH PHARMACOGENETIC OF METHOTREXATE IN RHEUMATOID ARTHRITIS PATIENTS – PRELIMINARY DATA
K. Hloch
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| 17:00 - 17:15 |
PREVALENCE OF DIETARY SUPPLEMENT USE IN PATIENTS IN PRE-OPERATIVE PERIOD
J. Strážnická
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