Program

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Wednesday 24. January 2018

Program of the conference in PDF

Lecture hall A

Joint session

Chairman: Prof. RNDr. Petr Solich, CSc.

8:30 - 8:45

Conference opening - introduction  

Prof. PharmDr. Tomáš Šimůnek, Ph.D., Dean of the Faculty of Pharmacy

 
8:45 - 9:45

Preparation of manuscript that is likely to be accepted in high end journal

Prof. František Švec

 

 

9:45 - 10:00

 

Coffee break (S2155)

 

 
10:00 - 10:30

Bead injection for (bio)chemical analysis

Prof. Marcela Segundo, University of Porto, Portugal

 
10:30 - 11:00

Environmental Pollutant Sensing on a Paper-Based Microfluidic Platform

Prof. Spas Kolev, University of Melbourne, Australia

 

 

Lecture hall A

Session 1 - Bioorganic and Pharmaceutical chemistry

Chairman: Prof. PharmDr. Martin Doležal, Ph.D.

12:30 - 12:45

PYRAZINAMIDE; NOT THE END OF THE STORY

G. Bouz

12:45 - 13:00

PREPARATION OF BENZODIAZINES WITH BRONCHODILATORY ACTIVITY

Z.R. Brožová

13:00 - 13:15

INTRAMOLECULAR TSUJI-TROST REACTION: NEW ROUTE TO HIGHLY SUBSTITUTED PYRANONES

Z. Brůža

13:15 - 13:30

NEW AZAPHTHALOCYANINE DARK QUENCHER USABLE IN POLYMERASE CHAIN REACTION

J. Demuth

13:30 - 13:45

THE NOVEL LEAD CANDIDATES FOR THE TREATMENT OF ORGANOPHOSHOROUS INTOXICATION

L. Gorecki

13:45 - 14:00 

NONTOXIC COMBRETAFURANONE ANALOGUES WITH HIGH IN VITRO ANTIBACTERIAL ACTIVITY

P. Horký

 

14:00 - 14:15

 

Coffee break (S2155)

 

14:15 - 14:30

SYNTHESIS OF NEW SULFONATED AZAPHTALOCYANINE AND ITS PHOTOPHYSICAL AND PHOTODYNAMIC PROPERTIES

J. Kollár

14:30 - 14:45

RHODANINE DERIVATIVES AS POTENTIAL AGENTS IN TREATMENT OF CHRONIC DIABETIC COMPLICATIONS

M. Kučerová

14:45 - 15:00

APPROACHES TO TOTAL SYNTHESIS OF NOSTOTREBIN 6

P. Matouš

15:00 - 15:15

FIGHTING MICROBIAL RESISTANCE – WHO IS GOING TO WIN?

O. Janďourek

 

Lecture hall B

Session 2 - Pharmacognosy and Toxicology of Natural Compounds

Chairman: Doc. Ing. Lucie Cahlíková, Ph.D.

12:30 - 12:45

AMARYLLIDACEAE ALKALOIDS AS POTENT GSK 3Β INHIBITORS

D. Hulcová

12:45 - 13:00

PHYTOCHEMICAL STUDY OF AMARYLLIDACEAE ALKALOIDS FROM NARCISSUS CV. CARLTON AND THEIR BIOLOGICAL ACTIVITY

A. Al Mamun

13:00 - 13:15

USE OF HPCCC FOR ISOLATING ASTAXANTHIN ESTERS FROM MICROALGAE HAEMATOCOCCUS PLUVIALIS

T. Fábryová

13:15 - 13:30

ISOLATION OF AMARYLLIDACEAE ALKALOIDS FROM ZEPHYRANTHES CITRINA

E. Kohelová

13:30 - 13:45

NMR ELUCIDATION OF ALKALOIDS ISOLATED FROM MAGNOLIA × SOULANGEANA

J. Maříková

 

13:45 - 14:00 

 

Coffee break (S2155)

 

14:00 - 14:15

PHYTOCHEMICAL ANALYSIS AND BIOLOGICAL ACTIVITY OF SELECTED MEDICINAL PLANTS WITH A FOCUS ON TESTING THE IMMUNOMODULATORY AND TYROSINASE ACTIVITIES

R. Vrabec

14:15 - 14:30

COPPER CHELATION ACTIVITIES OF ISOLATED COMPOUNDS FROM SILYBUM MARIANUM - STRUCTURE–ACTIVITY RELATIONSHIP

J. Karlíčková

14:30 - 14:45

ALKALOIDS OF VINCA MINOR L. AND THEIR EFFECT ON ACTIVITY OF SELECTED ENZYMES AS BENEFIT TO PROGRESS OF ALZHEIMER'S DISEASE

M. Ločárek

 

Lecture hall B

Session 3 - Pharmaceutical Technology

Chairman: Doc. PharmDr. Zdeňka Šklubalová, Ph.D.

15:00 - 15:15

MONOLAYER STUDY OF GLUCOSYLCERAMIDE-TO-CERAMIDE PROCESSING DURING SKIN BARRIER FORMATION

A. Nováčková

15:15 - 15:30

SILK FIBROIN AND ITS APPLICATION IN PHARMACEUTICAL TECHNOLOGY

J. Kožák

15:30 - 15:45

POLYMERIC NANOPARTICLES FOR INTRACELLULAR DELIVERY

J. Kubačková

15:45 - 16:00

STARLIKE POLYMERIC NANOPARTICULATE DRUG CARRIERS

J. Martiška

16:00 - 16:15

THE COMPRESSIBILITY STUDY OF PELLETS, POWDER MICROCRYSTALLINE CELLULOSE AND THEIR MIXTURES

Ž. Trpělková

16:15 - 16:30 

PRE-FORMULATION STUDIES OF LIQUISOLID SYSTEMS 

B. Vraníková

 

Thursday 25. January 2018

Lecture hall A

Session 4 - Pharmaceutical Analysis and Bioanalytical Chemistry

Chairmen: Prof. Marcela Segundo a Prof. Spas Kolev

8:30 - 8:45

UHPLC-MS/MS METHOD FOR MONITORING OF ARGININE METABOLISM IN CHRONIC WOUNDS

L. Javorská

8:45 - 9:00

DEVELOPMENT OF UHPLC METHOD FOR STABILITY STUDY OF OMEPRAZOLE SUSPENSIONS

K. Kučerová

9:00 - 9:15

CHROMATOGRAPHIC METHOD FOR THE ASSESSMENT OF VITAMIN B1 AND B6 DERIVATIVES IN WHOLE BLOOD

J. Jenčo

9:15 - 9:30

MIXED-MODE STATIONARY PHASES: EFFECT OF MOBILE PHASE TYPE AND ITS IONIC STRENGTH ON SEPARATION

L. Chrenková

9:30 - 9:45

ENRICHING OF PREPARED FLAT SHEET POLYSULFONE MEMBRANE FOR SEPARATION OF BIOMOLECULES WITH ANTIOXIDANT Α-TOCOPHEROL AND Α-LIPOIC ACID

M. Kohlová

9:45 - 10:00 

APPLICABILITY OF ULTRA-HIGH PERFORMANCE SUPERCRITICAL FLUID CHROMATOGRAPHY IN PHARMACEUTICAL QUALITY CONTROL

K. Plachká

 

10:00 - 10:15

 

Coffee break (S2155)

 

10:15 - 10:30

NANOFIBROUS POLYMERS AS EXTRACTION SORBENTS IN A SAMPLE PREPARATION

H. Raabová

10:30 - 10:45

AUTOMATED CONTINUOUS IN-SYRINGE DISPERSIVE LIQUID-LIQUID EXTRACTION AND BACK-EXTRACTION FOR THE DETERMINATION OF NITROPHENOLS IN SURFACE WATER

K. Fikarová

10:45 - 11:00

TESTING OF ELECTROSPUN NANOFIBERS FOR ON-LINE EXTRACTION IN CHROMATOGRAPHY SYSTEMS

M. Háková

11:00 - 11:15

STUDY OF SEPARATION BEHAVIOR OF SELECTED PHENOLIC ANALYTES

M. Hollá

11:15 - 11:30

DEVELOPMENT AND OPTIMIZATION OF UHPLC-MS/MS METHOD FOR ANALYSIS OF HCV ANTIVIRALS IN SAMPLES ARISED FROM CELL  EXPERIMENTS

J. Pavlík

11:30 - 11:45

UHPLC-MS/MS STABILITY STUDY OF SOBUZOXANE AND ITS ACTIVE FORM - ICRF-154 IN BIOLOGICAL MATRICES

P. Reimerová

Lunch break

12:45 - 13:00

IS SUPERCRITICAL FLUID EXTRACTION USEFUL TOOL FOR EXTRACTION OF BIOACTIVE COMPOUNDS?

V. Pilařová

13:00 - 13:15

UHPLC-MS/MS OF A NOVEL DEXRAZOXANE ANALOGUE- JAS -2 AND ITS PRODRUG

H. Piskáčková

13:15 - 13:30

TESTING OF NANOFIBERS AS NOVEL SORBENTS USING SEQUENTIAL INJECTION ANALYSIS SYSTEM

I. Šrámková

13:30 - 13:45

SEQUENTIAL INJECTION DETERMINATION OF THE HERBICIDE 2,4-DICHLOROPHENOXYACETIC ACID USING PRECONCENTRATION WITH A POLYMER INCLUSION MEMBRANE

L. Zelená

13:45 - 14:00

CANDIDA ALBICANS METABOLOMICS AND QUORUM SENSING IN HUMAN VAGINAL SWABS USING HIGH-RESOLUTION MASS SPECTROMETRY

P. Jakubec

14:00 - 14:15 

DEVELOPMENT OF CAPILLARY ELECTROPHORESIS METHOD
FOR THE CHARACTERIZATION OF PHARMACEUTICALS CONTAINING SILYMARIN COMPLEX

P. Riasová

14:15 - 14:30

UHPLC-MS/MS ANALYSIS OF ANTIVIRAL AGENT SOFOSBUVIR FOR STUDY OF ITS TRANSPORT MECHANISM

P. Svobodová

 

14:30 - 15:00

 

Coffee break (S2155)

 

 

Lecture hall A

Session 5 - Pathobiochemistry and Xenobiochemistry

Chairman: Prof. Ing. Barbora Szotáková, Ph.D.

15:00 - 15:15

GPXS, MICRORNA AND OBESITY ASSOCIATION

B. Hanousková

15:15 - 15:30

ACUTE TOXICITY OF R-PULEGONE AND R-MENTHOFURAN IN HUMAN LIVER SLICES

T. Zárybnický

15:30 - 15:45

IN VITRO STUDY OF DEXRAZOXANE ANALOG JAS 2 AND ITS WATER-SOLUBLE PRODRUGS

H. Jansová

15:45 - 16:00

ROLE OF HEXOSE-6-PHOSPHATE IN PROLIFERATION AND MIGRATION OF CANCER CELLS

H. Navrátilová

16:00 - 16:15

EVALUATION OF DRUG UPTAKE AND DEACTIVATION IN PLANT

 L. Raisová Stuchlíková

 

Lecture hall B

Session 6 - Pharmacology and Toxicology

Chairmen: Prof. PharmDr. František Štaud, Ph.D. a Doc. PharmDr. Přemysl Mladěnka, Ph.D.

8:30 - 8:45

OXYSTEROLS AFFECT ENDOGLIN EXPRESSION, INFLAMMATION AND DEVELOPMENT OF ENDOTHELIAL DYSFUNCTION IN HUMAN AORTIC ENDOTHELIAL CELLS 

M. Vicen

8:45 - 9:00

HIGH SOLUBLE ENDOGLIN LEVELS ACCOMPANIED BY MILD HYPERCHOLESTEROLEMIA AGGRAVATE ENDOTHELIAL DYSFUNCTION IN MOUSE AORTA

B. Vitverová

9:00 - 9:15

PHARMACOKINETIC INTERACTIONS OF NOVEL ANTICANCER DRUGS WITH ABC DRUG EFFLUX TRANSPORTERS AND CYTOCHROMES P450 

D. Vagiannis

9:15 - 9:30

THE IN VITRO AND EX VIVO TESTING OF ANTIVIRAL DRUGS EFFECT ON RHODAMINE123 INTESTINAL ABSOPTION

O. Martinec

9:30 - 9:45

ENTECAVIR TRANSPORT ACROSS PLACENTA AND THE ROLE OF NUCLEOSIDE TRANSPORTERS

S. Karbanová

 

9:45 - 10:00 

 

Coffee break (S2155)

 

10:00 - 10:15

THE INHIBITORY EFFECT OF ANTIRETROVIRAL DRUGS ON THE TRANSPORT OF L-CARNITINE IN HUMAN PLACENTA

R. Karahoda

10:15 - 10:30

NUCLEOSIDE TRANSPORTERS; ROLE IN PHARMACOKINETICS AND MECHANISMS OF REGULATION

L. Jirásková

10:30 - 10:45

RADIOLABELED MONOCLONAL ANTIBODY RAMUCIRUMAB: IN VITRO AND IN VIVO BINDING TO THE TARGET 

J. Janoušek

10:45 - 11:00

INVOLVEMENT OF FARNESOID X RECEPTOR IN NOVEL HUMAN CELLULAR MODEL OF STEATOHEPATITIS

A. Horvátová

11:00 - 11:15

ASSESSMENT OF THE STOICHIOMETRY OF IRON AND COPPER WITH DEHYDROSILYBIN A AND B

M. C. Catapano

11:15 - 11:30

THE INFLUENCE OF FLAVONOIDS METABOLITES ON PLATELET AGGREGATION

L. Applová

11:30 - 11:45

INTERGENDER DIFFERENCES IN THE VASOACTIVE EFFECT OF SELECTED ISOFLAVONOIDS AND THE THEIR COLONIC METABOLITES

T. Migkos

Lunch break

12:45 - 13:00

INVOLVEMENT OF DRUG TRANSPORTERS IN MARAVIROC TRANSPORT ACROSS PLACENTAL BARRIER

L. Ťupová

13:00 - 13:15

OVERCOMING DAUNORUBICIN RESISTANCE VIA ABCC1 AND AKR1C3 INHIBITION BY CYCLIN-DEPENDENT KINASE INHIBITORS

A. Šorf

13:15 - 13:30

NOVEL RAPID BUT PRECISE SPECTROPHOTOMETRIC SCREEENING METHOD FOR DETERMINIATION OF ZINC CHELATION

V. Tvrdý

13:30 - 13:45

CONSTITUTIVE ANDROSTANE RECEPTOR IN THE REGULATION OF XENOBIOTIC METABOLISM

J. Dušek

13:45 - 14:00

ASPECTS OF POST-TRANSCRIPTIONAL REGULATION OF PREGNANE X RECEPTOR

T. Smutný

14:00 - 14:15 

INTERACTIONS OF ANTIRETROVIRALS WITH DRUG TRANSPORTERS; ROLE IN THE PHARMACOKINETICS 

J. Řezníček

 

14:15 - 14:45

 

Coffee break (S2155)

 

 

Lecture hall B

 Session 7 - Clinical and Social Pharmacy

Chairmen: Prof. PharmDr. Jiří Vlček, Ph.D. a PharmDr. Daniela Fialová, PhD.

14:45 - 15:00

COLD, BUT RISING STAR OF VALUE ADDED MEDICINES IN EUROPE

J. Röder

15:00 - 15:15

THE BIOIMPEDANCE SPECTROSCOPY APPLICATION IN PREGNANT WOMEN WITH PRETERM PREMATURE RUPTURE OF MEMBRANES

 V. Josková

15:15 - 15:30

ADJUSTMENTS IN ENERGY EXPENDITURE AND SUBSTRATE OXIDATION DURING PREGNANCY

A. Patková

15:30 - 15:45

POTENTIALLY INAPPROPRIATE MEDICATION USE IN NURSING HOME RESIDENTS IN THE CZECH REPUBLIC: RESULTS FROM THE EU SHELTER PROJECT

S. Grešáková

15:45 - 16:00

DRUG UTILIZATION STUDY OF ANTICOAGULANTS 

S. Dvořáčková

16:00 - 16:15 

ANALYSIS OF FACTORS INFLUENCING THE RISK OF FALLS – PILOT RESULTS

J. Vosátka

16:15 - 16:30

POTENTIALLY INAPPROPRIATE MEDICATION USE („PIM“ USE) IN OLDER PATIENTS IN A TERTIARY CARE TEACHING HOSPITAL IN SOUTH INDIA: PREVALENCE AND RISK FACTORS

D.K. Bandari - prezentuje S. Grešáková

16:30 - 16:45

KNOWLEDGE OF DIFFERENT PHARMACY PROGRAM STUDENTS ON RATIONAL GERIATRIC PHARMACOTHERAPY 

A.S.Bhagavathula

16:45 - 17:00

CARDIOVASCULAR COMORBIDITIES AND RISK FACTORS IN ACCORDANCE WITH PHARMACOGENETIC OF METHOTREXATE IN RHEUMATOID ARTHRITIS PATIENTS – PRELIMINARY DATA

K. Hloch

17:00 - 17:15

PREVALENCE OF DIETARY SUPPLEMENT USE IN PATIENTS IN PRE-OPERATIVE PERIOD

J. Strážnická

 

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