Program

Conference program

( PDF version of program )


Short lectures marked with red asterisk * will be presented in Czech/Slovak language. Other lectures will be presented in English language.

Tuesday 9. 2. 2016, Lecture Hall A

8:20 

Opening of the conference

Doc. PharmDr. Tomáš Šimůnek, Ph.D., dean of the faculty

Prof. Ing. Vladimír Wsól, Ph.D., vice-dean of the faculty

 

 

Pharmaceutical Analysis Section

Chairman: Doc. RNDr. Dalibor Šatínský, Ph.D.; Doc. PharmDr. Petra Kovaříková, Ph.D.;
Doc. PharmDr. Radim Kučera, Ph.D.

8:30

Sequential Injection Manifold as a Tool for Automated Performance of Drug Permeation Studies
Zelená L., Hyršová L., Fibigr J., Pávek P., Sklenářová H.

Stability of Carfilzomib – UHPLC-PDA-QTOF Study of a Proteasome Inhibitor
Šesták V., Roh J., Klepalová L., Kovaříková P.

Molecularly Imprinted Polymers for Selective Extraction of Lovastatin from Food Samples and Elimination of Matrix Effects
Svoboda P., Sander D., Nováková L.

Development of HPLC-DAD Method for Anthocyanin Determination in Different Highbush Blueberry Cultivars
Šmídová B., Dostálová K., Židová P., Šatínský D., Matějíček A., Paprštein F.

09:40-10:00  Coffee break (room S2155)
 

New Extraction Spectrophotometric Methods for the Determination of Nitrogen Mustard (HN-3) in Acidic Environment
Rozsypal T., Halámek E., Kobliha Z.
NBC Defence Institute, University of Defence in Brno

Using Solid-Phase Microextraction for Plasma Protein Binding Study of DPC
Reimerová P., Stariat J., Kovaříková P.

Parallel Artificial Liquid Membrane Extraction – a New Approach for Selective Sample Preparation
Pilařová V., Skoglund Ask K., Gjelstad A., Nováková L., Pedersen-Bjergaard S.

The Testing of Nanofibres as Potential Sorbents in Solid Phase Extraction On-Line Coupled to HPLC
Parmová M., Chocholoušová Havlíková L., Šatínský D.

Development of HPLC Method for Determination of Eight Synthetic Food Dyes: Comparison of Monolithic and Fused-Core Column
Lhotská I., Stachová I., Šatínský D.

11:20-11:35 Coffee break (room S2155)
 

Development of UHPLC-UV Method for the Determination of Omeprazole in Oral Suspensions
Kučerová K., Reiská V., Matysová L., Kujovská-Krčmová L., Solich P.

Development of Extraction Procedure for the Determination of Thiamine and its Derivatives in Biological Fluids
Jenčo J., Kujovská Krčmová L., Solichová D., Solich P.

Development of HPLC-FD Method for Determination of Arginine and its Metabolites in Chronic Wound Fluids
Javorská L., Aufartová J., Piskáčková H., Kujovská Krčmová L., Solichová D., Solich P.

Quality Control of Food Supplements Available on the Czech Market Using Core-Shell Column Chromatography
Fibigr J., Šatínský D.

Determination of Artificial Colorants by Sequential Injection Chromatography Using Modern Monolithic Columns
Davletbaeva P.N., Chocholouš P., Solich P., Bulatov A.V.
Institute of Chemistry, Saint Petersburg State University, Russian Federation

A Novel Approach to the Lab-in-Syringe Technique. Determination of Ammonia in River Waters
Šrámková I., Horstkotte B, Sklenářová H., Solich P., Kolev S.

  Lunch
 

Pharmaceutical Technology Section

Chairman: Doc. PharmDr. Zdeňka Šklubalová, Ph.D.

Od 13:30

Influence of Superdisintegrants on the Properties of Tablets Composed from Different Starches
Stoniš J., Hurychová H., Skořepová Z., Ondrejček P., Svačinová P., Šklubalová Z.

A Biophysical Insight into a Disturbed Skin Lipid Barrier in β-Glucocerebrosidase Deficiency
Sochorová M., Staňková K., Pullmannová P., Kováčik A., Vávrová K.

Optimization of Fabrication of Nanoparticles with Hydrophilic Biologically Active Substances
Nguyenová J., Dittrich M., Šnejdrová E.

14:15-14:25  Coffee break (room S2155)
 

Biorelevant in-vitro Release Testing Methods for Controlled Release Parenterals: an Introduction
Kožák J., Rabišková M., Lamprecht A.

Evaluation of Transdermal Permeation Enhancers Based on Monosacharides
Kopečná M., Macháček M., Roh J., Vávrová K.

The Influence of Magnesium Stearate on the Flow and Shear Properties of Sorbitol*
Hurychová H., Stoniš J., Svěrák T., Šklubalová Z.

Tuesday 9. 2. 2016, Lecture Hall B 

 

Pharmacology and Toxicology Section

Chairman: Prof. PharmDr. Petr Pávek, Ph.D.;  Doc. PharmDr. Petr Nachtigal, Ph.D.

8:30

Different Substitutions of Isoflavonoids Core Influence Markedly Their Antiplatelet Potential
Applová L., Říha M., Karlíčková J., Filipský T., Macáková K., Hrdina R., Mladěnka P.

61,64Cu-(SCN)-Phosphinate-Immunoglobulin-G M75 and Their Biological Testing
Čepa A., Ráliš J., Marešová L., Kleinová M., Seifert D., Sieglová I., Král V., Lebeda O., Lázníček M.

Soluble Endoglin Effects in Aorta from Mice Fed High Fat Diet
Jezkova K., Rathouska J., Nemeckova I., Fikrova P., Dolezelova E., Varejckova M., Vitverova B., Tysonova K., Serwadczak A., Bernabeu C., Lopez-Novoa JM., Chlopicki S., Nachtigal P.

Differentiation and Epigenome Affecting Drugs Change Expression of Nucleoside Transporters in Placental Bewo Cell Line
Jirásková L., Červený L., Štaud F.

Ribavirin Transport Across Placenta and the Role of Nucleoside Transporters
Karbanová S., Červený L., Ptáčková Z., Štaud F.

9:50-10:10  Coffee break (room S2155)
 

Interactions of Intestinal Influx Transporter hOATP1A2 with Selected Flavonoids
Navrátilová L., Ramos Mandíková J., Trejtnar F.

Interactions of Antiretrovirals with the Main Placental Transporters
Ptackova Z., Cerveny L., Ceckova M., Reznicek J., Karbanova S., Greenwood S.L., Staud F.

Efavirenz Decreases Renal Excretion of Lamivudine through Inhibition of OCT1, OCT2 and MATE1 Drug Transporters
Reznicek J., Ceckova M., Staud F.

Response of Serum Inflammatory Mediators to Chemotherapy of Breast Cancer in Mice and Humans
Rozkydalová L., Mičuda S., Tomšík P., Grim J., Štaud F.

Regulation of OCT1 Transporter by Nuclear Receptor PXR in Different Hepatic Models
Hyrsova L., Moravcik S., Mandikova J., Pavek P., Trejtnar F.

11:30-11:40  Coffee break (room S2155)
 

Can Antidepressant Premedication Reduce Ischaemic-Reperfusion Induced Injury?
Vicen M., Gulač P., Stankovičová T.
Faculty of Pharmacy, Comenius University Bratislava

The Incidence of Dysrhythmias after Administration of Antipsychotic Olanzapine
Gulač P., Vicen M., Stankovičová T.
Faculty of Pharmacy, Comenius University Bratislava

Interaction of Keto and Acetylated Bile Acids with Farnesoid X (FXR), Vitamin D Receptor (VDR) and Pregnane X (PXR) Receptors
Carazo A., Hyršová L., Kudová E., Pávek P.

Soluble Endoglin Effects on Endothelial Cells in vitro
Varejckova M., Nemeckova I., Fikrova P., Dolezelova E., Vitverova B., Nachtigal P.

The Haemodynamic Effects of Flavonoid Metabolite 3-(3-Hydroxyphenyl)propionic Acid in Rat*
Pourová J., Najmanová I., Vopršalová M., Mladěnka, P.

Radiolabeling of anti-vegfr2 Monoclonal Antibody Ramucirumab with Technetium-99m*
Janoušek J., Bárta P., Trejtnar F.

   

Wednesday 10. 2. 2016, Lecture Hall A

 

Bioorganic and Pharmaceutical Chemistry Section

Chairman: Prof. PharmDr. Martin Doležal, Ph.D.; Doc. PharmDr. Kateřina Vávrová, Ph.D.

8:30

Intramolecular Tsuji-Trost Allylation – Enantioselectivity Outlook
Brůža Z., Kratochvíl J., Pour M.

Design and Synthesis of Novel 3,4-Diarylsubstituted Furanones for Growth-Inhibitory and Pro-Apoptotic Effect against Leukemia Cells
Horký P., Voráčová M., Vacek J., Pour M.

Nitro Group-Containing Heteroaromatic Compounds as Antitubercular Agents: Structure-Activity Relationships Study
Valášková L., Roh J., Karabanovich G., Němeček J., Stolaříková J., Vávrová K., Klimešová V., Hrabálek A.

Benzylderivatives of 3-Aminopyrazine-2-carboxamide: Synthesis and Anti-Infective Evaluation
Semelková L., Zitko J., Janďourek O., Paterová P., Konečná K., Doležal M.

Novel Biologically Active Quinazolines
Hrušková Z. R., Balmagambetov D., Vopršálová M., Pourová J., Pávek P., Špulák M. 

9:50-10:10  Coffee break (room S2155)
 

Signaling Role of Ceramides and their Metabolites in Mammalian Epidermis
Opálka L., Vávrová K.

Synthesis of Substituted Pyridines by Gold(I) Catalysis
Matouš P., Mikušek J., Janoušek M., Pour M.

Permeability and Microstructure of Model Lipid Membranes Containing 6-Hydroxyceramides
Kováčik A., Opálka L., Šilarová M., Maixner J., Vávrová K.

CO2 Sensors Using Phenol Substituted Azaphthalocyanines as the Fluorescent Indicator
Lochman L., Novakova V., Zimcik P., Borisov S. M.

11:20-11:40 Coffee break (room S2155)
 

Synthesis of Triclosan Derivates and Their Antimycobacterial Activity
Vosátka R., Krátký M., Vinšová J.

Synthesis of haemanthamine derivatives*
Němeček J., Hoštálková A., Chlebek J., Opletal L., Cahlíková L.

Salicylanilide-Oligotuftsin Conjugates: Synthesis and Biological Activity*
Krátký M., Baranyai Z.S., Bösze S.Z., Vosátka R., Vinšová J.

Synthesis of Azaphthalocyanine Containing Anionic Groups*
Kollár J., Zimčík P.
 

  Lunch
 

Section of Pharmacognosy and Toxicology of Natural Products

Chairman: Doc. Ing. Lucie Cahlíková, Ph.D.

13:30

Alkaloids from Narcissus cv. PROFESSOR EINSTEIN (Amaryllidaceae) – Isolation and Biological Activity
Breiterová K., Hošťálková A., Opletal L., Kuneš J., Cahlíková L.

Isolation of Alkaloids from Narcissus Dutch Master and their Biological Activities
Hulcová D., Chlebek J., Opletal L., Kuneš J., Cahlíková L.

Antiplatelet Effects of Flavonoids on Arachidonic Acid Based Pathway
Karlíčková J., Říha M., Filipský T., Macáková K., Hrdina R., Mladěnka P.

Transport Mechanisms in Cell Membrane of Red Clover
Kubeš J., Martin J., Kašparová M., Tůmová L.

Alkaloids of Vinca Minor L. and Their Effect on Activity of Selected Enzymes as Benefit to Progress of Alzheimer's Disease*
Ločárek M., Kuneš J., Hošťálková A., Chlebek J., Opletal L.

Wednesday 10. 2. 2016, Lecture Hall B

 

Pathobiochemistry and Xenobiochemistry Section

Chairman: Prof. RNDr. Lenka Skálová, Ph.D.; Doc. Ing. Barbora Szotáková, Ph.D.

8:30

Glutathione S-transferase in Rumen Fluke Calicophoron Daubneyi
Prchal L., Brophy P., Morphew R., Szotakova B.

In vitro Evaluation of Non-Agregating (Aza)phthalocyanines – Influence of Peripheral Substitution on Photodynamic Activity
Macháček M., Jedličková A., Firková P., Podhorská G., Půlkrábková M., Kollár J., Nováková V., Zimčík P., Šimůnek T.

Study of Extracellular Vesicles Production and Their Role in Pathogenesis of Candida Albicans Infection
Konecna K., Vejsova M., Jilek P., Klimentova J., Krocova Z., Benada O.

Newly Synthesized Analogs of Dexrazoxane – Initial In Vitro Characterization
Jirkovská A.

09:35-09:50   Coffee break (room S2155)
 

Iron Metabolism of the Tumour-Initiating Cells
Rychtarčíková Z., Lettlová S., Truksa J., Vinšová J.

Cyclin Dependent Kinase Inhibitors as Modulators and Substrates of ABC Transporters
Cihalova D., Ceckova M., Sorf A., Kucera R., Klimes J., Staud F.

Ribociclib and AZD5438 Modulate ABC Transporter-Mediated Multidrug Resistance In Vitro
Šorf A., Číhalová D., Čečková M., Štaud F.

First Identification of DHRS1 Enzyme as Specific Molecular Target of Anticancer Drug Oracin
Andrýs R., Zemanová L., Lenčo J., Wsól V.

11:00-11:15 Coffee break (room S2155)
 

A Promising Role of Human DHRS7 in the Metabolism of Retinoids and Steroids?*
Štambergová H., Zemanová L., Lundová T., Malčeková B., Šafr M., Wsól V.

Beta-Naphthoflavone Induction: Activities, Protein and RNA Levels of Drug Metabolizing Enzymes*
Lněničková K., Matoušková P., Skálová L., Szotáková B.

Expression Profile of DHRS1 in Human Tissues*
Andrejs J., Malčeková B., Lundová T., Štambergová H., Zemanová L., Šafr M., Wsól V.

Selected Sesquiterpenes from Myrica rubra Essential Oil Potentiated Accumulation and Efficacy of Doxorubicin in Cancer Cells.*
Ambrož M., Skarka A., Skálová L.
 

  Lunch
 

Section of Clinical and Social Pharmacy

Chairman: Prof. RNDr. Jiří Vlček, CSc.

Od 13:00

Medication Adherence to Severe Chronic Obstructive Pulmonary Disease (COPD)
Touskova T., Vytrisalova M., Koblizek V., Novotna B.

Negative Effects of Antiepileptic Drugs on Bone Health
Zimčíková E., Šimko J., Kremláček J., Talábová M., Fekete S.

Patient Access Gap: The delay between Marketing Authorization and Reimbursement Decision on New Drugs
Fuksa L., Vocelka M., Vytřísalová M.

Antibiotic Use Practices by Pharmacy Staff: A Cross-Sectional Study in Saint-Petersburg, Russian Federation
Belkina T., Duvanova N., Korolkova A., Duintjer Tebbens J., Vlcek J.

 

14:00-14:15 Coffee break (room S2155)
 

The Effect of Nutritional Support on the Body Fluid Volumes and on Clinically Significant Anthropometric Parameters in Critically Ill Patients*
Josková V., Patková A., Havel E., Kovařík M., Pavlickova Aimova P., Zadak Z., Hronek M.

The Effect of Energy and Nutritional Substrates Intake on Their Oxidation and the Energy Expenditure in Polytrauma Patients*
Patkova A., Joskova V., Havel E., Kovarik M., Pavlickova Aimova P., Zadak Z., Hronek M.

Safety of Direct Oral Anticoagulants in Patients with Chronic Renal Failure*
Dvorackova E., Stara D., Pavek P., Vlcek J.

Safety Assessment of Food Additives in Top-Selling Dietary Supplements in the Czech Republic*
Straznicka J., Pokladnikova J., Jahodar L.
 

   
  Short lectures marked with red asterisk * will be presented in Czech/Slovak language. Other lectures will be presented in English language.

 

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