Phytochemical Investigation of Schisandra chinensis (Turcz.) Baill. Leaves

Lubomír Opletal¹ (opletal@faf.cuni.cz), Markéta Křenková¹, Martin Jirkovský¹, Vladimír Hanuš², Viktor Voříšek³, Milan Pour¹, Helena Sovová⁴

¹ Department of Pharmaceutical Botany and Ecology, Charles University in Prague, Faculty of Pharmacy in Hradec Králové, Heyrovského 1203, CZ-500 05 Hradec Králové, Czech Republic
² J. Heyrovský Institute of Physical Chemistry, The Academy of Sciences of the Czech Republic, Dolejškova 3, CZ-182 23 Prague 8, Czech Republic
³ Faculty Hospital, Institute of Clinical Biochemistry and Diagnostics, Sokolská 581, CZ-500 05 Hradec Králové, Czech Republic
⁴ Institute of Chemical Process Fundamentals, The Academy of Sciences of the Czech Republic, Rozvojová 135, CZ-165 02 Prague 6, Czech Republic

Summary

As a part of systematic phytochemical studies of the vegetative parts of the taxon Schisandra chinensis basic extract from the leaves was prepared and further processed with diethyl ether and n-butanol. Ethereal extract was chromatographed on silica gel, and (E)-cinnamic acid kaempferol and quercetin were obtained as the main components. The compounds were found in this taxon for the first time. Both benzopyrane derivatives are most probably aglycones of flavonoid glycosides contained in n-butanol extract. The contained mixture of flavonoids is highly complex and individual components have not yet been separated in a preparative scale.