Einfluss von Eukalyptusöl auf die Konsistenz Hydrophober Zäpfchengrundlagen

Marie Musilová (musilova@faf.cuni.cz), Milan Řehula, Marta Čermáková, Hubert Žáček

Institut für Pharmazeutische Technologie der Pharmazeutischen Fakultät der Karls-Universität, Hradec Králové, Tschechische Republik

English Summary

The Effect of Eucalyptus Oil on the Consistence of Suppository Bases

The effect of eucalyptus oil on the content of solid and liquid parts in hydrophobic suppository base Adeps neutralis was studied by dilatometric method. After addition of eucalyptus oil, the original hard fat became more plastic. More pregnant than for melting temperature was the shifting of softening temperature. For critical temperatures beneath 30 °C, bad consistence can be expected. Liquid parts for concentrations higher than corresponds to the content of eucalyptus oil appear red at temperatures beneath 20 °C, namely for bases with higher melting temperature.